theweaselking: (Default)
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An extraordinary new scientific study, which for the first time documents marked improvement in Alzheimer’s disease within minutes of administration of a therapeutic molecule, has just been published in the Journal of Neuroinflammation.

This new study highlights the importance of certain soluble proteins, called cytokines, in Alzheimer’s disease. The study focuses on one of these cytokines, tumor necrosis factor-alpha(TNF), a critical component of the brain’s immune system. Normally, TNF finely regulates the transmission of neural impulses in the brain. The authors hypothesized that elevated levels of TNF in Alzheimer’s disease interfere with this regulation. To reduce elevated TNF, the authors gave patients an injection of an anti-TNF therapeutic called etanercept. Excess TNF-alpha has been documented in the cerebrospinal fluid of patients with Alzheimer’s.

“It is unprecedented that we can see cognitive and behavioral improvement in a patient with established dementia within minutes of therapeutic intervention,” said Griffin. “It is imperative that the medical and scientific communities immediately undertake to further investigate and characterize the physiologic mechanisms involved. This gives all of us in Alzheimer’s research a tremendous new clue about new avenues of research, which is so exciting and so needed in the field of Alzheimer’s.

(no subject)

Date: 2008-01-14 07:14 pm (UTC)
From: [identity profile] skola.livejournal.com
Is it bad that the first thing I thought of was "ok, Pratchett can write more books now"?

(no subject)

Date: 2008-01-14 07:21 pm (UTC)
From: [identity profile] opaqueplanet.livejournal.com
http://www.somethingpositive.net/sp12232007.shtml
Success!

(no subject)

Date: 2008-01-15 11:06 am (UTC)
From: [identity profile] publius1.livejournal.com
Ok, but who's the older British guy there?

(no subject)

Date: 2008-01-15 04:17 am (UTC)
From: [identity profile] thormation.livejournal.com
If it is, we are both going straight to Hell.

(no subject)

Date: 2008-01-14 07:29 pm (UTC)
From: [identity profile] torrain.livejournal.com
It is probably a bad sign that I spent the first thirty seconds *sure* this was a spoof.

(no subject)

Date: 2008-01-22 08:16 am (UTC)
From: [identity profile] lafinjack.livejournal.com
I figured it was going to be like that monkey hollering study.

(no subject)

Date: 2008-01-14 07:33 pm (UTC)
From: [identity profile] madcatwoman.livejournal.com
I hope and pray that this works and that it works well enough, with few side-effects, to become mainstream medicine. I have seen too many of my family struck down and lost before their eventual deaths.

(no subject)

Date: 2008-01-14 07:41 pm (UTC)
From: [identity profile] silmaril.livejournal.com
Pleasepleasepleaseplease? Please?

(no subject)

Date: 2008-01-14 07:45 pm (UTC)
From: [identity profile] the-flea-king.livejournal.com
This is the best news I've heard all day.

(no subject)

Date: 2008-01-14 08:49 pm (UTC)
ext_195307: (Self portrait)
From: [identity profile] itlandm.livejournal.com
While this is not immediately useful - puncturing people's spine is not something you can safely do at home or in a dirty, run-down nursery home with half-trained overworked nurses - its significance is in showing that someone finally got a lead on Alzheimer's. I'd be surprised if there isn't some oral medication or permanent cure (gene therapy?) before most of you spring chickens need it. Probably oral meds, since a permanent cure would not cause a steady cash flow from dependent patients over their extra decades of meaningful life, and is thus not worth investing in. Of course, capitalism may be dead before that, but just a hunch.

(no subject)

Date: 2008-01-14 09:13 pm (UTC)
From: [identity profile] madcatwoman.livejournal.com
"Spring chickens", eh? I'm older than you, sunbeam :-)
Still, a plethora of other conditions which lead to people living out their days in nursing homes will remain even if they can fix Alzheimer's.

(no subject)

Date: 2008-01-15 03:27 am (UTC)
From: [identity profile] jagash.livejournal.com
A similar hopeful story in medical science.

http://ca.news.yahoo.com/s/afp/science_health_medicine_heart_bioengineering_genetics

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